BOC SCIENCES

BOC Sciences engages in total-support business for research and development of carbohydrate synthesis with an established international reputation. Our services including design, synthesis and characterization of carbohydrate-based molecules from lab-research to scale-up production stages. By manipulations of protecting groups and functional groups of carbohydrates, specific coupling reactions and derivatizations can be well performed. BOC Sciences has developed numerous multi-step synthetic schemes, like the synthesis of oligosaccharide, glycan, sugar amino acid, glycopeptide, glycoconjugate, glucuronide, glycolipid and lipopolysaccharide to provide complex chemicals. BOC Sciences’ advanced capabilities in carbohydrate synthetic area, purification and identification has benefited our customers in academia, research institutions, biotechnology and pharmaceutical at all stages of R&D from basic research to clinical trials.

The maturing petroleum-based chemical industry, the pressures of environmental constraints and the explosive development of biotechnology have increased the interest in catalysis in enzymology. Enzymes are now an attractive proposition as catalysts for new classes of reagents and products, especially sugars, chiral synthons, metabolites and food components. Sometimes it is really hard to obtain the desired product from chemistry synthesis, especially when the scheme is very long. The best way to solve the problem is enzyme synthesis, semi-enzyme synthesis or fermentation. Enzymes are the proteins which catalyse reactions in living cells and they have evolved to cope with specific tasks in biosynthetic or metabolic reactions. One of the biggest advantage of using enzyme in organic synthesis is the good selectivity. With enzymes, enantioselectivities of 99%+ e.e. can be achieved when synthesis the chiral compounds.

Superparamagnetic iron oxide microbeads have broad applications in biomedicine, such as magnetic cell isolation and biomolecules purification, magnetic resonance imaging of diseased tissues, magnetic immunoassay, targeted delivery of drugs and antigens, hyperthermia aided chemo/radiotherapy, and so on. BOC Sciences offers high-quality superparamagnetic iron oxide microbeads. Our products include various-sized magnetic beads with different coupling groups for the conjugation of biomolecules. We have established a high-level platform that involves many scientists and a full set of instruments to guarantee the quality of our products and services and thereby help to facilitate your researches.

Disease models at molecular, cell and animal levels play critical roles in drug discovery. The biological activity of compounds sourced from chemical synthesis, natural products or biological molecules cannot be tested directly in the human body. The disease models which truthfully reflect the pathology of diseases serve effective and economical ways to explore the activity and corresponding mechanism of the compounds. Boc Sciences is applying more than 200 in vitro and in vivo bioassays of various disease models, including over 100 High-throughput screening (HTS) or high content screening (HCS) models, with the screening capacity reaching approximately 100,000 samples per day. Boc Sciences provides bioassays in: Cancers Cardiovascular diseases Neural system diseases Reproductive system diseases Respiratory system disease Metabolic diseases Infectious diseases