Germany
Manufacturer/ Producer
Germany
COMBER Pressofiltro® Series PF 100 - PF 10000 Pharmaceutical design COMBER Pressofiltro nutsche filters or filter dryers are versatile units designed for multipurpose production facilities. To meet the demanding requirements for filters used in the manufacture of pharmaceutical ingredients, the filters are designed to meet stringent cGMP and FDA guidelines. Special properties for the customer’s benefit: Excellent cleanability using CIP systems, simple validation Openable filter base provides for good access to the filter internals for cleaning and inspection Easily interchangeable filter plates, with flat, homogeneous filter surfaces for good cleanability and inspection Multilayer and/or conventional filter materials Good drying performance with special agitator design, large heat exchange areas Double mechanical seals, externally interchangeable, dry running contacting or non-contacting lift-off type seals as well as liquid lubricated seals
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COMBER Pressofiltro® - Series PF 2000 - PF 16000 Chemical design Chemical design Pressofiltro® agitated Nutsche filters, suction filters or filter dryers are versatile units equally suited for monoproduction applications and for multipurpose production facilities. Special properties for the customer’s benefit: Available as closed units with manhole access or with an openable filter base Multilayer and/ or conventional filter materials Good emptying characteristics due to narrow agitator to wall/ bottom clearances and a unique agitator blade design Shaft seal with externally accessible stuffing box
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COMBER Pressofiltro® Series PF 50 - PF 6000 Steam Sterilizable Design COMBER Pressofiltro steam sterilizable agitated Nutsche filter dryers are designed to maintain full sterility during the entire process, from inerting through slurry feeding and filtration, washing and drying to discharge of the dry product. CIP and SIP provide a very effective, safe and convenient form of sterilization, easy to automate and validate. Special properties for the customer’s benefit: With Cleaning-In-Place (CIP) and Sterilization-In-Place (SIP) systems designed for the automatic cleaning and disinfecting of the equipment Steam sterilizable filter dryer design assures steam reaches all parts of the filter dryer in contact with the product and air is not trapped in the unit during sterilization In compliance with cGMP and FDA guidelines, with vessel interior and all associated piping designed to prevent product adherence and to facilitate cleanability, fully drainable for clearance of condensate...
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COMBER Pressofiltro® Series PF 50 - PF 2000 with Containment System Pressofiltro® agitated Nutsche filters or filter dryers with containment system provide protection of the operators against hazardous materials and equally provide product or process safety against possible contamination from external particles. Special properties for the customer’s benefit: Containment systems (glove boxes) are designed to allow contamination free sampling, product discharge, heel removal and product pack-off into suitable containers Containment systems are available as passive, active, single chamber, two chamber and multiple chamber designs, all in compliance with cGMP and FDA guidelines Active isolator units are equipped with air handling systems and HEPA inlet and exhaust filters for containment levels down to 10 ng/m³ TWA The isolator design permits sampling, product discharge, pack-off, heel removal and filter cloth disposal in a single unit Sample and small items transfer using optional...
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COMBER Turbodry® - Series TD 0.8/1.1 - TD 40/60 The Turbodry agitated vacuum pan dryer has proven to be excellent for the drying of sensitive, pasty and other “diffcult” products that pass through a highly viscous stage during the drying process. The dryers have proven to be particularly suited for the drying of heat sensitive products as well as products with fragile crystal structure and thus sensitive to shear forces. Excellent product discharge and shortest cycle times. Special properties for the customer’s benefit: In compliance with cGMP and FDA guidelines, also in aseptic/ steam sterilizable versions Shortest possible drying times, suitable for the drying of sensitive, pasty, sticky and other “diffcult” products such as those turning highly viscous during the drying process Simultaneous axial and radial agitator movements permit uniform mixing of the entire product mass, without the formation of lumps or balls Double mechanical seal, dry running contacting or...
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COMBER Condry® - Series TDC 25 - TDC 15000 The Condry conical bottom agitated vacuum dryer was developed to process a wide variety of products. The machines have proven to be particularly suited for the drying of heat sensitive products as well as products with fragile crystal structure and thus sensitive to shear forces. The conical bottom allows for full product discharge characteristics. Special properties for the customer’s benefit: In compliance with cGMP and FDA guidelines, also in aseptic/ steam sterilizable versions Excellent product discharge performance with negligible product hold-up due to the conical vessel bottom, very close agitator to wall/bottom clearances and a unique agitator design The agitator permits uniform mixing of the entire product mass, without the formation of lumps or balls The surface area for heat transfer is maximized for optimum performance and cycle times Agitator supported by the top head, with the seal in contact with the vapors only Entirely...
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COMBER Pharmadry® - Series PH 50 - PH 4000 The Pharmadry vacuum paddle dryer with short drying times is well suited for the drying of freely flowing, sensitive pharmaceutical ingredients and fine chemicals. Designed to meet stringent cGMP and FDA guidelines. Special properties for the customer’s benefit: In compliance with cGMP and FDA guidelines, also in aseptic/ steam sterilizable versions Agitator supported at the rear, with externally exchangeable mechanical seal Entirely welded agitator design, without any bolts, without pockets and with all edges rounded for good cleanability Minimal build depth, thus very good accessibility for inspection and cleaning purposes Excellent cleanability using CIP systems, simple validation Available with separating wall between process and mechanical areas Double mechanical seal, externally interchangeable, dry running contacting or non-contacting lift-off type seals as well as liquid lubricated seals
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COMBER Termomix® Series TM 1000 - TM 40000 The Termomix vacuum paddle dryer/reactor is intended for monoproduction applications or bulk production facilities as mixer, reactor, precipitator and dryer. Special properties for the customer’s benefit: Economic, robust multipurpose machine for heavy industrial applications The agitator is supported on both ends providing excellent mixing characteristics, with externally interchangeable stuffing boxes or mechanical seals Large heating area resulting in an outstanding heat transfer rate by heating the vessel walls, the vessel ends as well as the agitator shaft and arms
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COMBER Pressofiltro® Series PF 5 - PF 100 Pilot Plant Pressofiltro pilot units are multipurpose tools for pilot plant or laboratory applications as well as for small scale production facilities. Versatile use of the equipment, cGMP compliant design, containment, effcient and complete cleanability, complete dischargeability, highest drying effciency, process safety and monitoring, ease of validation and a compact design are important requirements. Special properties for the customer’s benefit: In compliance with cGMP and FDA guidelines, also available in steam sterilizable and/ or aseptic designs Small pilot units are skid mounted including all drives, the required instrumentation and the hydraulics For easy access larger pilot units are mounted on a support column or post; the vessel base is mounted on a separate column to lower the base and displace it to the side Vessel base can be designed interchangeable for conversion to a conical bottom dryer or a Nutsche filter dryer...
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COMBER Pressofiltro® / Turbodry® Series PF/TD 5 - PF/TD 100 This Pilot Plant can either be used as Agitated Nutsche Filter/Filter Dryer or a Vacuum Dryer. Designed for processes in pilot plants, it is fully equipped for tests and trials and can as well be used for small scale production. Special properties for the customer’s benefit: Calculation, manufacture and design are in accord with Pressure Equipment Directive 97/23/EG or/and ASME U-stamp as well as with cGMP and FDA guidelines Approved for using in ATEX danger zone, group II 2G 2D (zones 1/ 21) Suitable as vacuum dryer, filter dryer or agitated nutsche filter Shaft seal through gland nut Device built on skid Control system protected against explosion (EEx-d) Options Multilayer PLC-system
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Sigmannser Weg 2
88239 Wangen Im Allgäu - Germany
Germany
DRYING CONTROL UNIT DA 4 QUBEThe overdrive for your low-pressure insulation drying operation Smaller, lighter and considerable time saving along the way – based on the Qube+’s development objective we now also designed an apposite drying control unit. The particularly compact drying control unit is tailored perfectly to the Qube+ and can be connected to it in just a few steps. In doing so, an elaborate intermediate hose connection with water separator is no longer necessary, this simplifies the installation and saves both time and material. DA 4 Qube: Perfect for the Qube+ – and it can be combined well with all other insulation dryers from your stock due to the optional DA adapter plate.
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WATER SEPARATOR WA 4I MULTIQUBEWater separator WA 4i for combination with MultiQube insulation layer dryers The new WA 4i is provided with an integrated micro filter system with low-maintenance magnetic lock filter compartment to take in micro filter cartridges with a threefold filter element. This makes the WA 4i a versatile integral solution with all pre-HEPA filter stages in only one device. Advantage: improved flow-optimized filter technology, quicker setup, decreased material and space requirements – no separate additional micro filter housings required. With respect to insulation drying of surfaces sized up to 40 m², no other model is quite fit to hold a candle to this separator, for despite its ultra-compact dimensions the WA 4i comes fully equipped with numerous practice-oriented detailed solutions, such as a construction yet easier to maintain, TTKwic quick couplings, cable holder, residual water drainage and much more.
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