Scientific research centres and laboratories - Import export

Progenus is committed to contributing to animal wellbeing. We take pride in recommending the appropriate genetic analyses for your animal’s breed. You can also use a DNA profile to certify its identity and parentage. All these analyses comply with the ISO17025 standard, for which we are accredited. We are also ISAG 2006 certified with a category 1 rings test result (more than 99% reliable). In addition to diseases, you can also carry out other tests to determine markers such as coat colour, hair length, short tail, etc. We are constantly developing our range of tests by keeping up to date with the latest scientific progress or participating ourselves via our Research department. If you need a specific test or wish to have our scientific opinion, we are at your disposal for any questions you may have.

Our services for research : - DNA services Development of simplex or multiplex real-time PCR tests Development of DNA extraction methods for all matrices Production of PCR kits (tubes or prefilled plates) as per ISO13485 Development of LAMP tests (isothermal DNA amplification) Development of PCR for sequencing applications (Sanger and NGS) Development of fragment analysis tests (fingerprint analysis – 22 markers) - Protein services Development of ELISA tests - Pathogen services Development of PCR methods for virus and bacteria detection Development of rapid bacteria and virus lysis.

https://www.invitro-connect.com/en - Your International Experts for Laboratory Testing and Regulatory Services - More than 80 test laboratories in our network - Product safety - Regulatory service - in vitro tests - All OECD tests for pharmaceuticals, chemicals, medical devices and cosmetics - in-house toxicologistes - Project management - Study monitoring --> complete services - all from one hand !!! --> contact@invitro-connect.com We would like to manage also your projects. Best regards Pascal Piller and the whole team of INVITRO-CONNECT GmbH #biocides #toxicological #chemicals #laboratory #regulatory #affairs #reach #projectmanagement #pharma #medical #study #devices #Labor #GLP #cosmetics

INVITRO-CONNECT GmbH: - Regulatory advice - All OECD laboratory tests - Phys-Chem / Tox / in vitro tests / Genotox / Ecotox, E-fate etc. - Personal project management - in-house toxicologists - Study monitoring - Study Summaries, IUCLID 6 - Dossier creation - MSDS etc. Benefit from an international, very well organized network: carefully selected experts, in-house toxicologists and more than 80 accredited test laboratories and service providers with over 20 years of experience in the industry. We are your competent partner for regulatory and toxicological issues, expert services, reports and all OECD laboratory tests We are also happy to be your reliable partner for your laboratory services and regulatory projects. Questions? -> contact@invitro-connect.com Your Mrs. Dr. Ute Hassmann and Your Mr. Pascal Piller

We offer you the following services: - Regulatory Advice - REACH Registration - Preparation of Registration Dossiers - Read Across - IUCLID - Robust Study Summaries - Chemical Safety Report / CSR - Toxicological Expertise - Optimal Test Strategy Development - REACH Testing: Tests and Studies acc. GLP - REACH Study Monitoring - SVHC Screening - Risk Assessment - REACh Compliance Service / REACh Auditing Service - REACH Material Safety Data Sheets We would also be happy to be your REACH service provider, who reliably looks after your REACH projects, just as we already do for many other satisfied customers. For more information please contact INVITRO-CONNECT GmbH. Fast Project Execution: personal - competent - reliable --> contact@invitro-connect.com REACH Service - All REACH laboratory tests - Phys-Chem / Tox / in vitro tests / Genotox / Ecotox, etc. - More than 80 test laboratories - Study monitoring, Regulatory Service, IUCLID 6, CSR etc.

INVITRO-CONNECT GmbH is your ideal partner and service provider for your projects in the field of life science for chemicals / REACH, pharmaceuticals, biocides, cosmetics and medical devices. We are the strong partner at your side who provides our tailor-made service modules according to your project requirements. You have the choice to individually select the modules that you urgently need in your projects from our modular service system. With our technical expertise and our customer-oriented approach, we fit in perfectly with your projects and processes, so that we form a team and nothing stands in the way of the project's success. The Modules can be individually and flexibly adapted for each project. For more information please contact INVITRO-CONNECT GmbH. INVITRO-CONNECT GmbH - Your International Experts for Laboratory Testing and Regulatory Services Fast Project Execution: personal - competent - reliable --> contact@invitro-connect.com

Medical Device Services / Medical Device Laboratory Testing INVITRO-CONNECT GmbH offers you: - General regulatory advice for medical devices - All regulatory examinations and tests under GLP - Project management and study monitoring - Medical Device Regulatory Service - Product testing for contained SVHC substances INVITRO-CONNECT offers you a complete service for the approval of medical devices according (EU) 2017/745 (Medical Device Regulation - MDR) / ISO 10993. From the development of an ideal test strategy to laboratory and project coordination, study monitoring, toxicological expertise and GLP inspections in the cooperation laboratories. We deliver the finalized test reports including the registration dossier - digitally and on paper, worldwide. Benefit from our diverse know-how, our experienced cooperation partners and an international, very well-organized network. Questions? -> contact@invitro-connect.com

- OECD 431 - Human Skin Corrosion: "In Vitro OECD 431: Reconstructed Human Epidermis Test Method, in vitro Test - Skin Corrosion in the regulatory hazard classification and labeling context is defined as the production of irreversible damage to skin, generally evident as necrosis through the epidermis and into the dermis, following a defined chemical exposure. The In Vitro Skin Corrosion Test is an in vitro, non-animal test designed to identify those chemicals and mixtures capable of inducing skin corrosion (UN GHS Category 11), and in some cases to partially subcategorize corrosives into UN GHS Sub-Categories 1A or 1B and 1C (ie., the current test methods do not effectively discriminate between UN GHS Sub-Categories 1B and 1C). For more information please contact INVITRO-CONNECT GmbH for assistance in developing specialized protocols for your test materials. INVITRO-CONNECT GmbH: Fast Project Execution: personal - competent - reliable --> contact@invitro-connect.com

- in vitro gene mutation study in bacteria: Ames Test OECD 471 - in vitro gene mutation study in mammalian cells: Mouse Lymphoma Assay (MLTK Assay) OECD 490 - in vitro gene mutation study in mammalian cells: HPRT test / OECD 476 - Micronucleus Assay in vitro (Human Lymphocytes or V79 cells) / OECD 487 - Chromosomal aberration Assay in vitro (Human Lymphocytes or V79 cells) / OECD 473 - Hen’s Egg Test – Induction of Micronuclei (HET-MN) - COMET Assay in different cell types - Cell Transformation Assay in Bhas Cells / OECD 231 (draft) - Mammalian Erythrocyte Micronucleus Test / OECD 474 / ISO 10993-3 - Combined Mammalian Erythrocyte Micronucleus Test with concurrent Alkaline Comet Assay in vivo OECD 474 & 489 - In vivo Mammalian Alkaline Comet Assay / OECD 489 - Unscheduled DNA synthesis (UDS) Test with Mammalian Liver Cells in vivo / OECD 486 - Mammalian Spermatogonial Chromosomal Aberration test / OECD 483 - Mammalian Bone Marrow Chromosomal Aberration test / OECD 475